Rets`epile Paul Matamane at al (National University of Lesotho)
Pharmacology OnLine 2, 233-240, 2019
Hexane, chloroform, ethyl acetate and methanolic extracts from leaves and stem-bark of Buddleja salviifolia were screened for their antioxidant activity by DPPH radical scavenging assay. B. salviifolia hexane leaves extract, B. salviifolia chloroform leaves extract, B. salviifolia ethyl acetate leaves extract and B. salviifolia methanolic leaves extract showed scavenging activity in the range of 10.04±3.97 to 17.45±3.64, 41.73±1.68 to 47.46±1.36, 25.81±1.34 to 47.43±4.25 and 44.88±1.50 to 50.34±3.09%, respectively, at various concentrations. B. salviifolia hexane stem-bark extract, B. salviifolia chloroform stem-bark extract, B. salviifolia ethyl acetate stem-bark extract and B. salviifolia methanolic stem-bark extract showed scavenging activity in the range of 2.51±1.22 to 32.30±3.16, 27.90±3.74 to 51.91±1.43, 5.30±2.13 to 34.89±3.59 and 19.86±3.23 to 57.24±1.23%, respectively, at various concentrations. The IC50 values of all these extracts were also determined and found to be in the range of 450 to> 3000 µg/mL. The positive control, ascorbic acid, showed an IC50 value of< 200 µg/mL.
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